REILLY ASSOCIATES
 WPAI References

General Health




Academy for Health and Productivity Measurement. Health risks and work performance. Academy Briefs. 

Ciconelli RM, Soarez PC, Kowalski CC, Ferraz MB.  The Brazilian Portuguese version of the Work Productivity and Activity Impairment: General Health (WPAI-GH) Questionnaire. Sao Paulo Med J. 2006;124(6):325-332. 

Evers KE, Castle PH, Prochaska JO, Prochaska JM. Examining relationships between multiple health risk behaviors, well-being, and productivity (.). Psychol Rep. 2014 Jun;114(3):843-53. 

Gawlicki MC, Reilly MC, Popielnicki A, Reilly K.  Linguistic validation of the US Spanish Work Productivity and Activity Impairment questionnaire, general health version (WPAI:GH). Value in Health. 2006; 9(3);199-204.

Gawlicki MC, Reilly MC, Popielnicki A, Reilly K.  Linguistic validation of the US Spanish Work Productivity and Activity Impairment questionnaire, general health version (WPAI:GH). Presented ISPOR Tenth Annual International Meeting, May 17, 2005, Washington, DC.

Lenneman J, Schwartz S, Giuseffi DL, Wang C. Productivity and health: an 
2011;53(1):55-61.

Letvak S, Buck R.  Factors influencing work productivity and intent to stay in nursing.  Nursing Economics.  May-June, 2008.

Reilly MC, Zbrozek AS, Dukes EM.  The validity and reproducibility of a work productivity and activity impairment instrument.  PharmacoEconomics 1993; 4(5):353-65.
Hepatitis
Dibonaventura MD, Wagner JS, Yuan Y, L'italien G, Langley P, Ray Kim W. The
impact of hepatitis C on labor force participation, absenteeism, presenteeism and
non-work activities. J Med Econ. 2011 Mar 9. [Epub ahead of print]

El Khoury AC, Vietri J, Prajapati G. The Burden of Untreated Hepatitis C Virus
Infection: A US Patients' Perspective. Dig Dis Sci. 2012 Jun 5. 

Liu GG, Dibonaventura MD, Yuan Y, Wagner JS, L'italien GJ, Langley P, Kamae I. The burden of illness for patients with viral hepatitis C: evidence from a national survey in Japan. Value Health. 2012 Jan;15(1 Suppl):S65-71.

Malaguarnera G, Pennisi M, Gagliano C, Vacante M, Malaguarnera M, Salomone S, Drago F, Bertino G, Caraci F, Nunnari G, Malaguarnera M. Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial. Hepat Mon. 2014 May 5;14(5):e11608. 

Perrillo R, Rothstein KD, Rubin R, Alam I, Imperial J, Harb G, Hu S, Klaskala W. Comparison of quality of life, work productivity and medical resource utilization of peginterferon alpha 2a vs the combination of interferon alpha 2b plus ribavirin as initial treatment in patients with chronic hepatitis C. J Viral Hepat. 2004 Mar;11(2):157-65. 

Samp JC, Perry R, Piercy J, Wood R, Baran RW. Patient health utility, work productivity, and lifestyle impairment in chronic hepatitis C patients in France. Clin Res Hepatol Gastroenterol. 2014 Nov 11.

Younossi ZM, Jiang Y, Smith NJ, Stepanova M, Beckerman R. Ledipasvir/ sofosbuvir regimens for chronic hepatitis C infection: Insights from a work productivity economic model from the United States. Hepatology. 2015 Feb 23.

Younossi ZM, Stepanova M, Afdhal N, Kowdley KV, Zeuzem S, Henry L, Hunt SL, Marcellin P. Improvement of health-related quality of life and work productivity in chronic hepatitis C patients with early and advanced fibrosis treated with ledipasvir and sofosbuvir. J Hepatol. 2015 Mar 17. 

Younossi ZM, Stepanova M, Henry L, Gane E, Jacobson IM, Lawitz E, Nelson D, Gerber L, Nader F, Hunt S. Effects of Sofosbuvir-Based Treatment, With and Without Interferon, on Outcome and Productivity of Patients With Chronic Hepatitis C. Clin Gastroenterol Hepatol. 2013 Dec 6. pii: S1542-3565(13)01838-7. 

Younossi ZM, Stepanova M, Nader F, Jacobson IM, Gane E, Nelson D, Lawitz E, Hunt SL. Patient-reported outcomes in chronic hepatitis C patients with cirrhosis treated with sofosbuvir-containing regimens. Hepatology. 2014 Apr 8. 

Younossi ZM, Stepanova M, Zeuzem S, Dusheiko G, Esteban R, Hezode C, Reesink HW, Weiland O, Nader F, Hunt SL. Patient-Reported Outcomes Assessment in Chronic Hepatitis C Treated with Sofosbuvir and Ribavirin: The VALENCE Study. J Hepatol. 2014 Apr 5. 


Headache
Katzelnick D.  Prevalence and burden of illness in migraine in an HMO population. Presented 42nd Annual Scientific Meeting of the American Headache Society, Montreal, June 23-26, 2000.
Irritable Bowel Syndrome/ Chronic Constipation
Bracco A, Reilly MC, McBurney C, Ambegaonkar B. Burden of irritable bowel syndrome with constipation on health care resource utilisation, work productivity and activity impairment and quality of life in France, Germany and United Kingdom.  Presented United European Gastroenterology Week, Oct 15-19, 2005, Copenhagen, Denmark.

Bracco A, Reilly MC, McBurney C, Ambegaonkar B.  Burden of irritable bowel syndrome with constipation on health care resource utilization, work productivity and activity impairment and quality of life. Presented 13th World Congress of Gastroenterology,  Montreal, Canada September 10-14, 2005.

Bushnell DM, Galani C, Martin ML, Ricci JF, Reilly MC, Patrick DL.Validation of EDC versions of IBS-QOL, EQ-5D and WPAI-IBS questionnaires.Value in Health 2005 (8):383.  (Presented ISPOR 10th Annual International Meeting, Washington DC, May 15-18, 2005.)

Bushnell DM, Reilly MC, Galani C, Martin ML, Ricci JF, , Patrick DL, McBurney C.  Validation of EDC versions of IBS-QOL, EQ-5D and WPAI-IBS questionnaires.   Value in Health. 2006; 9(2):98-105.

Dean BB, Aguilar D, Barghout V, Kahler KH, Frech F, Groves D, Ofman JJ.  Impairment in work productivity and health-related qulaity of life in patients with IBS.  Amer J Man Care 2005 (11); S17-26.:

Dibonaventura MD, Prior M, Prieto P, Fortea J. Burden of constipation-predominant irritable bowel syndrome (IBS-C) in France, Italy, and the United Kingdom. Clin Exp Gastroenterol. 2012;5:203-12. doi: 10.2147/CEG.S35568. Epub 2012 Nov 8.

Dibonaventura M, Sun SX, Bolge SC, Wagner JS, Mody R. Health-related quality of life, work productivity and health care resource use associated with constipation predominant irritable bowel syndrome. Curr Med Res Opin. 2011 Sep 28. [Epub ahead of print]

Engsbro AL, Begtrup LM, Kjeldsen J, Larsen PV, de Muckadell OS, Jarbøl DE, Bytzer P. Patients Suspected of Irritable Bowel Syndrome-Cross-Sectional Study Exploring the Sensitivity of Rome III Criteria in Primary Care. Am J Gastroenterol. 2013 Feb 19. 

Neri L, Basilisco G, Corazziari E, Stanghellini V, Bassotti G, Bellini M, Perelli I, Cuomo R; LIRS Study Group. Constipation severity is associated with productivity losses and healthcare utilization in patients with chronic constipation. United European Gastroenterol J. 2014 Apr;2(2):138-47

Pare P, Lam S, Balshaw R, Keown P, Khorasheh S, Barbeau M, McBurney.  Patient characteristics (irritable bowel syndrome with constipation [IBS-C]): baseline results from LOGIC (Longitudinal Outcomes study of GI symptoms in Canada).  Presented American College of Gastroenterology October 30, 2005, Honolulu, Hawaii.

Paré P, Gray J, Lam S,Balshaw R, Khorasheh S, Barbeau M, Kelly S, McBurney CR. Health-Related Quality of Life, Work Productivity, and Health Care Resource Utilization of Subjects with Irritable Bowel Syndrome: Baseline Results from LOGIC (Longitudinal Outcomes study of GastroIntestinal symptoms in Canada), a Naturalistic Study. Clin Ther. 2006:28(10):1726-35.

Reilly MC, Barghout V, McBurney CR, Niecko TE.  Effect of tegaserod on work and daily activity in IBS with constipation.  Aliment Pharmacol & Ther 2005; 22:373-380. 

Reilly MC, Barghout V, McBurney CR.  Effect of tegaserod on work and daily activity: results from ZENSAA..  Presentated 13th World Congress of Gastroenterology, Montreal, Canada September 10-14, 2005.

Reilly MC, Barghout V, Ruegg P, Pecher E, Ricci J-F.  Tegaserod significantly reduces work productivity loss and daily activity impairment in patients with IBS with constipation.  Am J Gastroenterol 2004;99(10):S241.

Reilly MC, Bracco A, Ricci J-F, Santoro J, Stevens T.  The validity and accuracy of the Work Productivity and Activity Impairment questionnaire - irritable bowel syndrome version (WPAI:IBS).   Aliment  Pharmacol Ther 2004; 20:459-467.

Reilly MC, Bracco A, Geissler K, Johanson J, Kahler KH.  Impact of irritable bowel syndrome (IBS) on work productivity and daily activities. Presentated 69th Annual Meeting American College of Gastroenterology,: Orlando FL, 3 Nov 2004.

Reilly MC, McBurney CR.  Responsiveness of the Work Productivity and Activity Impairment Questionnaire for Irritable Bowel Syndrome with Constipation (WPAI:IBS-C) to clinically meaningful change.  Presentated American College of Gastroenterology October 30, 2005, Honolulu, Hawaii.

Reilly MC, McBurney CR,. Bracco A.  Work absenteeism in irritable bowel syndrome (IBS): measuring days versus hours missed.  Presented ISPOR 8th Annual European Congress, Nov 6-8, 2005, Florence, Italy. 

Sun SX, Dibonaventura M, Purayidathil FW, Wagner JS, Dabbous O, Mody R. Impact
of Chronic Constipation on Health-Related Quality of Life, Work Productivity, and
Healthcare Resource Use: An Analysis of the National Health and Wellness Survey. 
Dig Dis Sci. 2011 Mar 6. [Epub ahead of print] 
Calleja JL, Bixquert M, Maldonado J; for the SINERGE Study Group. Impact of Nocturnal Heartburn on Quality of Life, Sleep, and Productivity: The SINERGE Study. Dig Dis Sci. 2006 Jul 29; [Epub ahead of print] 
Hypertension
HIV/ AIDS
Dacosta Dibonaventura M, Gupta S, Cho M, Mrus J. The association of HIV/AIDS
treatment side effects with health status, work productivity, and resource use.  AIDS Care. 2012 Jan 31. [Epub ahead of print] 

Jayathunge MP, Bowanwatanuwong C, Maek-A-nantawat W, Pitisuttithum BP.
Psychosocial burden of abnormal pap smears among HIV-infected women at Chon Buri 
hospital, Thailand. Southeast Asian J Trop Med Public Health. 2010;41(1):224-34.
Inflammatory Bowel Disease
Burisch J, Cukovic-Cavka S, Kaimakliotis I, Shonová O, Andersen V, et al. Construction and validation of a web-based epidemiological database for inflammatory bowel diseases in Europe An EpiCom study. J Crohns Colitis. 2011 Sep;5(4):342-9. Epub 2011 Apr 2.

Cohen BL, Zoëga H, Shah SA, Leleiko N, Lidofsky S, Bright R, Flowers N, Law M, Moniz H, Merrick M, Sands BE. Fatigue is highly associated with poor health-related quality of life, disability and depression in newly-diagnosed patients with inflammatory bowel disease, independent of disease activity. Aliment Pharmacol Ther. 2014 Apr;39(8):811-22. 

Leong RW, Huang T, Ko Y, Jeon A, Chang J, Kohler F, Kariyawasam V. Prospective validation study of the International Classification of Functioning, Disability and Health score in Crohn's disease and ulcerative colitis. J Crohns Colitis. 2014 Mar 21.

Michael MD, Bálint A, Lovász BD, Gulácsi L, Strbák B, Golovics PA, Farkas K, Kürti Z, Szilágyi BK, Mohás A, Molnár T, Lakatos PL. Work disability and productivity loss in patients with inflammatory bowel diseases in Hungary in the era of biologics. Eur J Health Econ. 2014 May 16.
Gout
Dibonaventura MD, Andrews LM, Yadao AM, Kahler KH. The effect of gout on health-related quality of life, work productivity, resource use and clinical outcomes among patients with hypertension. Expert Rev Pharmacoecon Outcomes Res. 2012 Dec;12(6):821-9

Khanna P, Nuki G, Bardin T, Tausche AK, Forsythe A, Goren A, Vietri JT, Khanna D. Tophi and frequent gout flares are associated with impairments to quality of life, productivity, and increased healthcare resource use: Results from a cross-sectional survey. Health Qual Life Outcomes. 2012 Sep 22;10(1):117. [Epub ahead of print]

Spaetgens B, Wijnands JM, van Durme C, van der Linden S, Boonen A. Cost of Illness and Determinants of Costs Among Patients with Gout. J Rheumatol. 2014 Nov 15. 

Lupus
Garris C, Oglesby A, Sulcs E, Lee M. Impact of systemic lupus erythematosus on burden of illness and work productivity in the United States. Lupus. 2013;22 (10): 1077-86. 

Gordon C, Isenberg D, Lerstrøm K, Norton Y, Nikaï E, Pushparajah DS, Schneider
M. The substantial burden of systemic lupus erythematosus on the productivity and
careers of patients: a European patient-driven online survey. Rheumatology
(Oxford). 2013 Sep 18.

Holloway L, Humphrey L, Heron L, Pilling C, Kitchen H, Højbjerre L, Strandberg-Larsen M, Hansen B. Patient-reported outcome measures for systemic lupus erythematosus clinical trials: a review of content validity, face validity and psychometric performance. Health Qual Life Outcomes. 2014 Jul 22;12(1):116.